Protein name:
Gamma-glutamyltranspeptidase 1 (GGT 1) ;
Alternative:
3.4.19.13;Glutathione hydrolase 1 ) ;Gamma-glutamyltransferase 1 ;3.4.19.14;Leukotriene-C4 hydrolase ) ;
CD:
CD224 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Heterodimer composed of the light and heavy chains. The active site is located in the light chain.
Function:
Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MKNRFLVLGL | VAVVLVFVII | GLCIWLPTTS | GKPDHVYSRA | AVATDAKRCS |
100:
EIGRDMLQEG | GSVVDAAIAS | LLCMGLINAH | SMGIGGGLFF | TIYNSTTRKA |
150:
EVINAREMAP | RLANTSMFNN | SKDSEEGGLS | VAVPGEIRGY | ELAHQRHGRL |
200:
PWARLFQPSI | QLARHGFPVG | KGLARALDKK | RDIIEKTPAL | CEVFCRQGKV |
250:
LQEGETVTMP | KLADTLQILA | QEGARAFYNG | SLTAQIVKDI | QEAGGIMTVE |
300:
DLNNYRAEVI | EHPMSIGLGD | STLYVPSAPL | SGPVLILILN | ILKGYNFSPK |
350:
SVATPEQKAL | TYHRIVEAFR | FAYAKRTMLG | DPKFVDVSQV | IRNMSSEFYA |
400:
TQLRARITDE | TTHPTAYYEP | EFYLPDDGGT | AHLSVVSEDG | SAVAATSTIN |
450:
LYFGSKVLSR | VSGILFNDEM | DDFSSPNFTN | QFGVAPSPAN | FIKPGKQPLS |
500:
SMCPSIIVDK | DGKVRMVVGA | SGGTQITTSV | ALAIINSLWF | GYDVKRAVEE |
550:
PRLHNQLLPN | TTTVEKNIDQ | VVTAGLKTRH | HHTEVTPDFI | AVVQAVVRTS |
568:
GGWAAASDSR | KGGEPAGY
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Pig
Polyclonal Antibody for Rat GGT 1
Polyclonal Antibody for Rat GGT 1
Polyclonal Antibody for Rat GGT 1
Polyclonal Antibody for Rat GGT 1
Monoclonal Antibody for Rat GGT 1
Monoclonal Antibody for Rat GGT 1
Monoclonal Antibody for Rat GGT 1
Monoclonal Antibody for Rat GGT 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 31-43 AND 380-388
tissue :
Kidney .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM;SEQUENCE REVISION TO 66-135
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-21
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-18
strain :
Wistar .
tissue :
Liver .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-9
tissue :
Kidney .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 4-568
tissue :
Kidney .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 64-136
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 30-47 AND 380-402
tissue :
Kidney .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GENE ORGANIZATION;ALTERNATIVE PROMOTER USAGE
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION;SIALIC ACID CONTENT
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION